Cellular protein homeostasis (proteostasis) plays an essential role in regulating the folding. sequestration. and turnover of misfolded proteins via a network of chaperones and clearance factors. Previous work has shown that misfolded proteins are spatially sequestered into membrane-less compartments in the cell as part of the proteostasis process. https://www.tonerparts.shop/product-category/adf-pick-roll/
Clearing the JUNQ: the molecular machinery for sequestration, localization, and degradation of the JUNQ compartment
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