Mono-allelic germline disruptions of the transcription factor GATA2 result in a propensity for developing myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). affecting more than 85% of carriers. How a partial loss of GATA2 functionality enables leukemic transformation years later is unclear. This question has remained unsolved mainly due to the lack of informative models. https://safeersappliancers.shop/product-category/neff-c17ms32h0b-n90-built-in-60cm-electric-single-oven-stainless-steel/